4126 Southwest Fwy Ste 1200, Houston, TX 77027

CALL US! (346) 440-4824
  • 4126 Southwest Fwy Ste 1200 Houston, TX 77027
CALL US (346) 440-4824
Aesthetic Treatments

lipodissolve Houston TX

Clinically targeted fat cell destruction with no incisions, no anesthesia, and no surgical downtime.
Dr. Rodriguez has spent more than three decades refining fat reduction techniques at Rodriguez Rejuvenation, and lipodissolve sits at the intersection of that clinical expertise and modern non-surgical innovation. Lipodissolve, also known as injection lipolysis, uses a carefully formulated blend of phosphatidylcholine and deoxycholate injected directly into targeted fat deposits, triggering controlled breakdown and natural elimination of fat cells. The result is measurable reduction in specific problem areas without the recovery demands of surgical liposuction. As a board-certified plastic surgeon who pioneered minimally invasive body contouring in Houston, Dr. Rodriguez brings surgical-level precision to every injection lipolysis treatment he performs.
Book a Consultation
Call (346) 440-4824
Board Certified   •   Practicing since 2009   •   Houston, TX
Lipodissolve Fat Loss
30–60 Min
In-office procedure, no anesthesia required
3–7 Days
Return to normal activity within one week
Board Certified
Board-certified plastic surgeon with 30+ years in body contouring
How it works

Recovery and Results

Over the following four to eight weeks, your body metabolizes and eliminates the disrupted fat cells through the lymphatic system. Most patients require two to four treatment sessions spaced four to six weeks apart to achieve their target reduction.
01

Consultation and Mapping

Before your procedure session, Dr. Rodriguez maps the precise injection sites and calculates the appropriate dosing based on the size and density of each fat deposit. No two treatment maps are identical because no two patients present the same anatomy.
02

Customized Injection Planning

Before your procedure session, Dr. Rodriguez maps the precise injection sites and calculates the appropriate dosing based on the size and density of each fat deposit. No two treatment maps are identical because no two patients present the same anatomy.
03

In-Office Treatment

Using a fine-gauge needle, Dr. Rodriguez delivers the lipodissolve solution in a grid pattern across the marked treatment zone, typically over 20 to 45 minutes depending on the area size. Patients experience a mild stinging and pressure sensation during injection, which resolves within minutes of completion.
04

Recovery and Results

Over the following four to eight weeks, your body metabolizes and eliminates the disrupted fat cells through the lymphatic system. Most patients require two to four treatment sessions spaced four to six weeks apart to achieve their target reduction.
Ideal candidate

Lipodissolve Fat Loss may be a good fit if you

  • Carrying isolated fat deposits in areas like the submental region, inner thighs, flanks, or lower abdomen that have not responded to sustained diet and exercise
  • At or near a healthy body weight with a BMI generally under 30 and seeking refinement rather than significant volume reduction
  • Medically cleared and not taking anticoagulant medications, as blood thinners significantly increase bruising risk and require a mandatory pre-treatment pause
  • Uncomfortable with surgical procedures or unwilling to accept the downtime associated with liposuction, and have realistic expectations about the gradual, incremental nature of injection lipolysis results
  • Free of active skin infections, autoimmune conditions affecting fat or connective tissue, or pregnancy, all of which are contraindications to phosphatidylcholine-based injection treatments
Candidacy is confirmed during an in-person consultation with Dr. Rodriguez.
What to expect

Before, during, and after

Before
Discontinue aspirin, ibuprofen, naproxen, and any fish oil or vitamin E supplements at least seven days before your session to reduce bruising. Avoid alcohol for 48 hours prior. No fasting is required, but arrive well-hydrated and with the treatment area clean and free of lotions or topical products.
During
No sedation or local anesthesia is used for lipodissolve. Dr. Rodriguez works methodically through the mapped injection grid, and most patients describe the sensation as a sharp pinch followed by a mild burning that fades quickly. A full session typically takes 30 to 60 minutes depending on the number of zones being treated that day.
After
Expect immediate swelling, redness, and tenderness in the treated area, which is a normal inflammatory response and a sign the solution is working. Some patients experience firmness or nodularity beneath the skin for two to three weeks as fat cells break down. Avoid heat exposure, vigorous exercise, and massage of the treated area for the first 48 to 72 hours.
Recovery

What the first weeks may look like

●
Days 1–3
Swelling, bruising, and localized tenderness peak within the first 48 hours and are most pronounced during this window. Over-the-counter acetaminophen manages discomfort; avoid NSAIDs as they increase bruising.
●
Days 4–7
Bruising begins to yellow and fade, and swelling starts to soften. Most patients return to desk work and light daily activity by day four or five, though the treated area remains sensitive to pressure.
●
Weeks 2–4
Any residual firmness or lumpiness under the skin typically resolves by the end of week three as the inflammatory phase completes. You will not see final contour changes yet, as fat elimination through the lymphatic system is still in progress.
●
Weeks 5–8
Visible reduction in the treated fat deposit becomes apparent for most patients between weeks five and eight after each session. Patients returning for a follow-up session will be reassessed by Dr. Rodriguez at the six-week mark before scheduling additional treatment.
Before & after

Real patients of Dr. Rodriguez

View the full gallery
The gallery below features real patients of Dr. Rodriguez who have completed lipodissolve treatment at Rodriguez Rejuvenation in Houston. All photographs are shared with documented written patient consent and represent actual outcomes, though individual results vary based on anatomy, number of sessions completed, and adherence to post-treatment guidelines. These images are intended to give you an honest reference point, not a guarantee of identical results.
Individual results vary. Photos should only be used with documented patient consent.
HCG
Before
HCG
After
Consultation

Request your Lipodissolve Fat Loss consultation

Tell us what you would like to achieve. Our care team will follow up to help you plan the next step.
Your information is kept private and used only to respond to your request.

What patients say about Lipodissolve Fat Loss

Frequently Asked Questions about Lipodissolve Fat Loss

Clear answers to common questions before your consultation.
How many lipodissolve sessions will I need to see results?
Most patients require two to four sessions per treatment zone to achieve meaningful and lasting reduction. Sessions are spaced four to six weeks apart to allow full inflammatory resolution and accurate reassessment before the next round of injections.
Pricing at Rodriguez Rejuvenation is based on the number of zones treated per session and the total number of sessions in your plan, so costs are quoted individually after your consultation. We offer patient financing options to help spread the cost of your full treatment course.
Lipodissolve using phosphatidylcholine and deoxycholate has a well-documented safety profile when administered by an experienced physician using appropriate dosing and injection technique. Known risks include prolonged swelling, uneven fat reduction, skin irregularity, and in rare cases, skin ulceration if the solution is injected too superficially. Choosing a board-certified plastic surgeon with deep knowledge of subcutaneous anatomy significantly reduces these risks.
Kybella is an FDA-approved synthetic deoxycholate specifically indicated for submental fat, while lipodissolve uses a compounded phosphatidylcholine and deoxycholate formulation that can be applied to a broader range of body areas. Dr. Rodriguez will recommend the appropriate option based on your anatomy and treatment goals during your consultation.
Fat cells destroyed through injection lipolysis do not regenerate, so the reduction in the treated area is permanent as long as your body weight remains stable. Significant weight gain after treatment can expand remaining fat cells in adjacent areas, which is why lipodissolve works best as a refinement tool rather than a weight loss solution.
Lipodissolve is specifically designed for localized, well-defined fat deposits and is not an effective option for patients with diffuse or high-volume fat accumulation. If your goals require more significant volume reduction, Dr. Rodriguez will discuss whether surgical liposuction or a medical weight loss program would better serve your needs.
If you have a specific area of fat that has not responded to lifestyle changes, a consultation with Dr. Rodriguez is the right first step. He will evaluate your anatomy in person, give you a candid assessment of what injection lipolysis can realistically achieve for you, and build a treatment plan tailored to your body. Call our Houston office or request your consultation online to get started.
Book a Consultation
Call (346) 440-4824
From the blog

Further reading

All articles

Related treatments

Mesotherapy

Micro-injections of vitamins, enzymes, and active compounds that target localized fat deposits and improve skin quality.
Learn more

Mesobotox

Diluted Botox injected into the skin surface to minimize pores, reduce oil production, and tighten superficial texture.
Learn more

Cellulite Removal

Minimally invasive treatment that severs fibrous bands beneath the skin to smooth dimpled cellulite texture.
Learn more