4126 Southwest Fwy Ste 1200, Houston, TX 77027

CALL US! (346) 440-4824
  • 4126 Southwest Fwy Ste 1200 Houston, TX 77027
CALL US (346) 440-4824
Medical Weight Loss

semaglutide Houston TX

Clinically proven appetite regulation that produces real, measurable weight loss under physician supervision.
Dr. Rodriguez has spent over three decades helping Houston patients reshape their bodies, and semaglutide has become one of the most clinically significant tools in that work. As a board-certified plastic surgeon who also leads a comprehensive medical weight loss program, he brings a level of anatomical understanding and outcome-focused thinking to GLP-1 therapy that most weight loss clinics simply cannot offer. Semaglutide works by mimicking a naturally occurring gut hormone that regulates appetite and blood sugar, helping patients achieve meaningful, sustained weight loss without surgical intervention. At Rodriguez Rejuvenation, your semaglutide program is supervised directly by Dr. Rodriguez, not handed off to a nurse coordinator or virtual assistant.
Book a Consultation
Call (346) 440-4824
Board Certified   •   Practicing since 2009   •   Houston, TX
Semaglutide Injection
15–30 min
Weekly in-office or self-administered injection
None
Resume normal activity immediately after each injection
Board Certified
Plastic surgeon with 30+ years in body contouring and medical aesthetics
How it works

Monitoring and Adjustment

Dr. Rodriguez tracks your weight, body composition, and side effect profile throughout the program, adjusting dosage and adding nutritional guidance as needed. Results are assessed at regular intervals so the plan evolves with you.
01

Comprehensive Consultation

Semaglutide is started at a low dose and titrated gradually over several weeks to minimize side effects and help your body acclimate. Dr. Rodriguez sets your escalation schedule based on your individual response, not a one-size protocol.
02

Personalized Dosing Plan

Semaglutide is started at a low dose and titrated gradually over several weeks to minimize side effects and help your body acclimate. Dr. Rodriguez sets your escalation schedule based on your individual response, not a one-size protocol.
03

Weekly Injections Begin

Injections are administered subcutaneously, typically in the abdomen, thigh, or upper arm, and take less than a minute. Most patients learn to self-administer at home after the first session, with ongoing check-ins to monitor progress and tolerability.
04

Monitoring and Adjustment

Dr. Rodriguez tracks your weight, body composition, and side effect profile throughout the program, adjusting dosage and adding nutritional guidance as needed. Results are assessed at regular intervals so the plan evolves with you.
Ideal candidate

Semaglutide Injection may be a good fit if you

  • Have a BMI of 27 or above with at least one weight-related health condition such as hypertension, prediabetes, or elevated cholesterol
  • Have a BMI of 30 or above without comorbidities and have not achieved lasting results through diet and exercise alone
  • Are not pregnant, not planning pregnancy in the near term, and have no personal or family history of medullary thyroid carcinoma or MEN2 syndrome
  • Want to reduce body fat ahead of or following a surgical procedure such as liposuction or a Brazilian butt lift to optimize outcomes
  • Are managing insulin resistance or early metabolic dysfunction and want a GLP-1 protocol supervised by a physician rather than a telehealth platform
Candidacy is confirmed during an in-person consultation with Dr. Rodriguez.
What to expect

Before, during, and after

Before
Before starting semaglutide, Dr. Rodriguez orders baseline labs including fasting glucose, HbA1c, lipid panel, thyroid function, and a comprehensive metabolic panel. Patients should disclose all current medications, including insulin and other glucose-lowering agents, as semaglutide can potentiate hypoglycemia in certain combinations. No fasting is required before injections, but starting on a day when you can rest if needed is advisable during the first few weeks of dose escalation.
During
Each injection takes under one minute and is virtually painless when administered correctly. Dr. Rodriguez or his clinical team demonstrates proper injection technique during your first visit, covering site rotation and storage so you are fully confident administering doses at home. Patients remain awake and fully alert throughout; there is no anesthesia and no recovery period in the office.
After
Most patients notice mild nausea, reduced appetite, or a feeling of fullness in the first week or two, particularly after dose increases. These effects typically diminish as your body adjusts to each new dose level. Staying well hydrated and eating smaller, lower-fat meals in the early weeks significantly reduces GI discomfort.
Recovery

What the first weeks may look like

●
Weeks 1–4
The starting dose of 0.25 mg is intentionally low and most patients tolerate it well. Appetite reduction is subtle at this stage; the goal is tolerability, not aggressive weight loss.
●
Weeks 5–8
Dosage increases to 0.5 mg and most patients begin noticing a meaningful reduction in hunger and portion size. Some patients report nausea with dose escalation; this generally resolves within several days.
●
Months 2–4
Dose continues to escalate toward the therapeutic range of 1 mg to 2.4 mg depending on the formulation and response. Consistent weight loss becomes measurable at this stage, typically in the range of one to two pounds per week for adherent patients.
●
Months 4 and Beyond
Patients who reach their target weight work with Dr. Rodriguez on a maintenance or taper strategy to preserve results. Those combining semaglutide with surgical body contouring discuss optimal timing for procedures once a stable weight plateau is reached.
Before & after

Real patients of Dr. Rodriguez

View the full gallery
The results shown below are from actual patients of Dr. Rodriguez who have completed a supervised semaglutide program at Rodriguez Rejuvenation in Houston. Each photo set represents that individual’s response to treatment, and results vary based on starting weight, adherence, duration, and other personal health factors. All images are shared with documented patient consent and are intended to give you an honest sense of what medically supervised GLP-1 therapy achieves, not a guaranteed outcome.
Individual results vary. Photos should only be used with documented patient consent.
HCG
Before
HCG
After
Consultation

Request your Semaglutide Injection consultation

Tell us what you would like to achieve. Our care team will follow up to help you plan the next step.
Your information is kept private and used only to respond to your request.

What patients say about Semaglutide Injection

Frequently Asked Questions about Semaglutide Injection

Clear answers to common questions before your consultation.
How much does semaglutide cost at Rodriguez Rejuvenation, and does insurance cover it?
Pricing depends on the formulation, dosage, and program structure, and Dr. Rodriguez’s team reviews all of that during your consultation. Most insurance plans do not cover semaglutide for cosmetic weight loss, though coverage exists for patients with qualifying diagnoses such as obesity or type 2 diabetes. Financing options are available through the practice for patients paying out of pocket.
Most patients begin noticing reduced appetite within the first two to four weeks, but visible weight loss typically becomes consistent after the dose reaches therapeutic levels, usually around months two to three. Clinical trials show an average weight reduction of 15 to 17 percent of body weight over 68 weeks for patients on the highest dose of semaglutide. Individual results vary based on starting weight, adherence, and diet.
The most common side effects are gastrointestinal: nausea, constipation, bloating, and occasional vomiting, particularly during dose escalation. More serious but rare risks include pancreatitis, gallbladder disease, and, based on animal studies, a theoretical risk of thyroid C-cell tumors, which is why semaglutide is contraindicated in patients with a personal or family history of medullary thyroid carcinoma. Dr. Rodriguez reviews your complete medical history specifically to screen for these risks before prescribing.
Ozempic and Wegovy both contain semaglutide as the active ingredient; the difference is the approved dosing range and the indication, with Wegovy approved specifically for chronic weight management at higher doses. Rodriguez Rejuvenation works with licensed compounding pharmacies and brand-name sources depending on availability and patient need. Dr. Rodriguez clarifies exactly what formulation you are receiving and why during your consultation.
Yes, and this is actually one of the more clinically thoughtful ways to approach body contouring. Patients who reach a stable weight on semaglutide before liposuction or a BBL often see better surgical outcomes because the remaining fat deposits are more defined and the body is at a realistic maintenance weight. Dr. Rodriguez coordinates timing between your weight loss program and any planned surgical procedures to ensure you are operating from a stable baseline.
Clinical data shows that many patients regain a portion of the lost weight after discontinuing semaglutide, because the drug addresses an ongoing physiological process rather than a temporary condition. Dr. Rodriguez is transparent about this from the start. The practice helps patients develop realistic long-term strategies, which for some patients means a maintenance dose and for others means transitioning to surgical contouring once a stable weight is achieved.
If you are ready to have a real clinical conversation about whether semaglutide is appropriate for your health and your goals, Dr. Rodriguez is the right place to start. His team sees patients for in-person consultations at the Houston practice, where you will leave with a clear picture of your options, not a sales pitch. Call or submit a request online to schedule your consultation.
Book a Consultation
Call (346) 440-4824
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